Hemophilias

Discuss hemophilia including but not limited to:

  • Pathophysiology
  • Epidemiology
  • Physical exam findings
  • Differential diagnoses and rationale
  • Management plan to include diagnostic testing, medications if applicable, follow-up plans, and referrals if needed
  • About one page long
  • At least 3 references, no more than 5 years old

Requirements: About one page long

 

Answer preview

Hemophilia is a bleeding disorder that makes the blood not clot appropriately after an injury or surgery. The disorder is inherited, mainly due to insufficient blood-clotting proteins (Tiede, Collins, Knoebl, Teitel, Kessler, et al., 2020). However, some other people have no family history of the disease, and so the disorder is mainly caused by changes in genes located at the X chromosomes that make the clotting protein needed in the blood to form clotting after a cut. This change in genes can prevent the blood clotting protein not to function as required. Some of the factors that cause acquired hemophilia are pregnancy, cancer, autoimmune conditions, or multiple sclerosis.

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