Neurotransmission

Rapid Review focus Psychoactive drug; Cocaine

Select a psychoactive drug Cocaine that is of pharmacological interest, but not one you will review as part of your Critical Review or one that was included in your previous Rapid Review. For this paper, you may choose drugs of abuse; however, the paper must focus on the pharmacology of the drug and not on the social or addictive aspects. If you focus on addiction and social impact, your paper will not receive credit.

In addition to the text, research a minimum of three peer-reviewed articles published within the last five years on your selected drug. Prepare a three-page summary of the drug using the PSY630 Rapid Review Example paper (Links to an external site.) as a guide.

In your Rapid Review, analyze and explain the pharmacological aspects of the drug as they relate to the following: neurotransmitters affected, receptors, route of administration, half-life, doses, side effects, drug interactions, contraindications, and other important facets of the drug. Explain these aspects of the drug in terms of the psychiatric disorders indicated for the drug and the issue(s) associated with that use. If there is no accepted therapeutic use for the drug, evaluate and describe the actions of the drug with regard to the abuse process.

The paper:

  • Must be three to five double-spaced pages in length, excluding title page and references page, and it must be formatted according to APA style as outlined 7th edition.

Paragraph layout for paper:

Description of Drug, Neurotransmitters and Receptors Affected
Route of Administration, Half-life, Dosage
Side Effects, Drug interactions, Contraindications
Psychiatric Disorders Indicated for the Drug OR The Abuse Process of the Drug
Conclusion

Requirements: APA | Analytical Review | 3 pages, Double spaced

Here is a link to the Textbook that I have Chapter 7 covers the psychoactive drug Cocaine;

Advokat, C. D., Comaty, J. E., & Julien, R. M. (2018). Julien’s primer of drug action: A comprehensive guide to the actions, uses, and side effects of psychoactive drugs (14th ed.). Retrieved from https://vitalsource.com

Answer preview

Cocaine dosage varies and depends on the vascularity of the tissue, area to be anesthetized, individual tolerance, and the technique of the anesthesia. Dosage usage should be decreased for children, the elderly, and debited patients. Cocaine Hydrochloride solution can be administered by means of spray, cotton applicator, or installed into the cavity. In the nasal mucosal area, the range of the dose is 40-160 mg to be anesthetized and the procedure to be performed. A maximum of the two soaked cotton or rayon may be used in each nasal cavity, with a total of 160 mg (4% solution) of the cocaine Hydrochloride. Although cocaine is used for medical purposes, it also has side effects. Cocaine Hydroxide solution causes sloughing of the cornea epithelium, causing clouding and occasionally ulceration of the cornea (Atigari, Uprety, Pasternak, Majumdar, & Kivell. (2019).

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