Mitochondrial disorders

you should come to understand the relationship between abnormal physiology and disease. So, when you are discussing a disease, you need, first of all, to have an understanding of the normal physiology of the organ or organ system that your study will concern.

Then, once you have that understanding, you will describe what pathophysiological changes occur in that organ or organ system and how these lead to the clinical expression of the disorder you are describing in your paper.

To this end, your research paper will allow you to illustrate your understanding of the relationship of normal and abnormal physiology. Your study can be of a patient with a particular disease or disorder that interests you especially, or it can be one that you learned about through your contacts with patients or even friends or family, or yourself.

You are already aware that each disease has a particular etiology, or cause (sometimes, the etiology is not known), and follows a sequence of developments (pathogenesis) that reflects physiologic change (disruption of homeostasis) occurring in the patient throughout the progression of the disease. The changes that occur in the patient during the development of the disease