Nonsteroidal anti-inflammatory drugs

Sally is a 50-year-old female who has been a jogger for several years. She has recently been diagnosed with osteoarthritis. She has been taking ibuprofen for 3 months but states that “it does not help” and hurts her stomach. The health care provider prescribes celecoxib (Celebrex) 100 mg orally twice a day.

  1. What is the first-line therapy for osteoarthritis and the mechanism of action?
  2. Sally expresses concern about all the recent news about heart problems and celecoxib (Celebrex). What information should be included in a teaching plan to help her understand about taking celecoxib and the benefits and risks?
  3. Ibuprofen and celecoxib are both nonsteroidal anti-inflammatory drugs. Explain how they are similar and different

Submission Instructions:

  • Your initial post should be at least 500 words, formatted and cited in current APA style with support from at least 2 academic sources.

Answer preview

Celecoxib is a category of NSAID drugs used for pain relief and inflammation in patients with OA, arthritis and painful menstruations (Isola, Matarese, Ramaglia, Cicciù, & Matarese, 2019). The benefit of the drug is that it is associated with fewer gastrointestinal bleeding risks than other medicines under NSAIDs. However, patients who take NSAID drugs other than acetaminophen, such as Celecoxib, have a higher risk of stroke or heart attack. Such events happen abruptly when one is not aware and can lead to death. I would advise Sally to take Celecoxib under her doctor’s guidelines. Also, she should explain to her doctor about her family history with heart diseases or if she smokes because they increase the chances of heart failure. In addition, if the doctor prescribes the medication and experiences certain side effects, she should immediately rush to the hospital.

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