The final assignment for this class will be a 10-page critical review of the drug treatment for a psychiatric disorder (broadly defined to include psychological and neurological disorders as well). The review will use peer-reviewed sources to evaluate the current drug treatment modalities for the selected disorder and determine the adequacy of those treatments. The paper will be evaluated on the inclusion of the following information:
Theory
Evaluate the predominant theory or theories regarding the biological basis of the disorder. Explain the disorder in terms of pertinent neurotransmitter and receptor theories and describe the pertinent evidence of their involvement. Analyze the neurotransmitter systems in terms of the involved receptors and the use receptor agonists and antagonists in the treatment of the disorder receptor. Include information on the anatomic changes to the central nervous system as appropriate to the topic.
Treatment
Evaluate drug therapies for treating the disorder based on the current understanding of the biological basis of the disorder and the corresponding behavioral effects of the disorder. Explain pharmacokinetics and pharmacodynamics in relation to the disorder and corresponding drug treatment. Describe any side effects and adverse effects of the drug treatment and their biological basis, including issues related to contraindications, interactions, drug metabolism, and elimination. In addition, explain risks, benefits, and ethical implications for high-risk and exceptional treatment conditions.
Conclusion
Summarize theories of psychiatric disease as they relate to principles of drug action within the chosen topic. Evaluate advantages and disadvantages of the current theory of the disorder and its treatment and evaluate any controversies regarding ethical and/or risk-benefits perspectives associated with the current treatment. Describe possible areas for future research.
Attention Students: The Masters of Arts in Psychology program is utilizing the Pathbrite portfolio tool as a repository for student scholarly work in the form of signature assignments completed within the program. After receiving feedback for this Critical Review, please implement any changes recommended by the instructor, go to Pathbrite (Links to an external site.)Links to an external site. and upload the revised Critical Review to the portfolio. (Use the Pathbrite Quick-Start Guide (Links to an external site.)Links to an external site. to create an account if you do not already have one.) The upload of signature assignments will take place after completing each course. Be certain to upload revised signature assignments throughout the program as the portfolio and its contents will be used in other courses and may be used by individual students as a professional resource tool. See the Pathbrite (Links to an external site.)Links to an external site. website for information and further instructions on using this portfolio tool.
AD affects many sites of the brain including the frontal-parietal cortex, temporal cortex, entorhinal cortex and the hippocampus. It further affects the subcortical nuclei. It and the subcortical nuclei. This is the sites where there is the synaptic damage, the synaptic loss as well as abnormalities of the mitochondrial in this region. The early events of his disease are the abnormalities and dysfunction. The cellular changes and the pathological conditions in this region of the brain are among others, the formation and the building up of Aβ and Aβ plaques. At the same time, there is the tangling of the neurofibrillary and hyperphosphorylated tau. The main occurrences in the brain that then cause the cognitive decline are the damage to synaptic and synapses of the brain.
