pharmacological aspects of drug interactions

Note: You papers should be well structured as per the instructions.

Rapid Review Psychoactive drug use Cannabis

In your Rapid Review, analyze and explain the pharmacological aspects of the drug as they relate to the following: neurotransmitters affected, receptors, route of administration, half-life, doses, side effects, drug interactions, contraindications, and other important facets of the drug. Explain these aspects of the drug in terms of the psychiatric disorders indicated for the drug and the issue(s) associated with that use. If there is no accepted therapeutic use for the drug, evaluate and describe the actions of the drug with regard to the abuse process. The paper must focus on the pharmacology of the drug and not on the social or addictive aspects. If you focus on addiction and social impact, your paper will not receive credit.


In addition to the text, research a minimum of three peer-reviewed articles published within the last five years on your selected drug. Prepare a three-page summary of the drug using the PSY630 Rapid Review Example paper (Links to an external site.) as a guide.

Must be three to five double-spaced pages in length, excluding title page and references page, and it must be formatted according to APA style.

Requirements:   |   .doc file | APA | Analytical Review | 3 pages, Double spaced

Text book Chapter 9 covers Cannabis

Advokat, C. D., Comaty, J. E., & Julien, R. M. (2018). Julien’s primer of drug action: A comprehensive guide to the actions, uses, and side effects of psychoactive drugs (14th ed.). Retrieved from

Answer preview

There are various metabolic and pharmacodynamic interactions between medical cannabis and other pharmaceuticals. Metabolism of exogenous cannabinoids indicates hepatic cytochrome 450 (CYP450), isoenzymes 2C9, and 3A4 play an essential role in the primary metabolism cannabinoids (Asadi, 2019). Limited clinical trials are showing the effects of exogenous cannabinoids on the metabolism of other medications. Despite this limitation, drug interaction data may be obtained from prescribed information from cannabinoids-derived pharmaceutical products. Additive pharmacodynamic effects are possible when cannabis is administered with other agents having similar psychological effects. In addition, smoking cannabis increases theophylline metabolism.

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